Women were about 6 percent of the total enrollment by the mid-1890's. Bachelor Degrees had been awarded to women in Architecture (1888), Chemistry (1873), Biology (1889) Physics (1888), General Science (1885), and Geology (1891)
Many alumnae were practitioners in the fields ESR helped form.
- Mabel Clapp (Mrs. Frederick T.) Lord '98 : pioneer in public health planning. Active in alumnae affairs. (Right) Mabel Clapp Lord and Mary Baker Strong '97, geology field trip 1896
- Alice Gertrude Bryant '86 one of the first two women admitted to the American College of Surgeons (1916). Invented surgical instruments. Active in alumnae affairs.
- Mary Elizabeth Jones '85 Biology: doctor, Johns Hopkins Medical School
- Lilley Miller Kendall '92 Chemistry: assistant to ESR and Prof. Drown, State Department of Inland Waterways
- Isabel Bevier '98 Chair of Department of Home Economics, UCLA
- Katherine Blunt '03
- Grace MacLeod '01
The 1916 register showed that 10% of the early MIT alumnae were or had been college professors or instructors, including:
- Margaret E. Maltby '91, Barnard ((Right)
- Bertha Millard Brown '92, Vassar
- Grace Langford '00, Barnard
- Mary Louise Foster '87, Wellesley
- Charlotte Almira '90, Smith
- Elizabeth Spaulding Mason '93, Smith
Many were architects.
- Lois Lilley Howe '88 (Right): founded two architectural firms. One of the first woman fellows of the American Institute of Architects. Active in alumnae affairs.
- Sophia (Hayden) Bennett '90: won the design competition for the Women's Pavilion built at the Columbian Exposition (1893)
- Mabel Babcock '08: designed the gardens at the MIT president's house in Cambridge, taught at Wellesley
- Lydia Weld '02 was the first woman to receive a degree from the engineering school, in naval architecture and marine engineering
- Ida Annah Ryan '05 was the first woman to be awarded a master degree, and the first to win architecture's travelling scholarship